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Systemic Sclerosis and MCTD (Overlap Syndrome)

Systemic Sclerosis 

Includes
  • SLE
  • Polymyositis
  • Systemic Sclerosis 
  • high titer of anti-U1-ribonucleoprotein (RNP) antibodies
    • SLE patients can have anti-U1 RNP ab. This does not mean it is a MCTD by default
Clinical Features
  • Similar to each component of Diseases
  • Arthritis is usually non-erosive however, RA like erosive arthritis can occur



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