Systemic Sclerosis and MCTD (Overlap Syndrome)

Systemic Sclerosis  Megaduodenum in Systemic Sclerosis NEJM 2015 Includes SLE Polymyositis Systemic Sclerosis  high titer of anti-U1-ribonucleoprotein (RNP) antibodies SLE patients can have anti-U1 RNP ab. This does not mean it is a MCTD by default Clinical Features Similar to each component of Diseases Arthritis is usually non-erosive however, RA like erosive arthritis can occur “To Be or Not To Be,” 10 yrs After: Evidence for MCTD as a Distinct Entity Seminars in Arthr and Rheum 2012 “To Be or Not To Be,” 10 yrs After: Evidence for MCTD as a Distinct Entity Seminars in Arthr and Rheum 2012 “To Be or Not To Be,” 10 yrs After: Evidence for MCTD as a Distinct Entity Seminars in Arthr and Rheum 2012 “To Be or Not To Be,” 10 yrs After: Evidence for MCTD as a Distinct Entity Seminars in Arthr and Rheum 2012