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Syncope

  • SYNCOPE: Cardiogenic / Orthostatics / Neurocardiogenic / Psychogenic / rule out Seizure - Perform and document orthostatics BP your self - 
    • Cardiogenic 
      • Arrythmia as a primary cause
        • Bradycardia
        • Tachycardia
        • Drug Induced 
      • Structural Heart Disease
        • Cardiac
          • Valvular Disease
          • Ischemic
          • Myocardial
          • Pericardial
        • Other
          • PE
          • Aortic Dissection
          • Pulmonary HTN

      • Alarming features
        • Syncope due to exertion
        • while lying down 
        • SOB
        • CHF
        • Low Hgb
        • Low BP
    • Orthostatics Hypotension
      • Definition: HR 2015
        • Vasovagal syncope is defined as a syncope syndrome that usually 
          • (1) occurs with upright posture held for more than 30 seconds or with exposure to emotional stress, pain, or medical settings; 
          • (2) features diaphoresis, warmth, nausea, and pallor;
          • (3) is associated with hypotension and relative bradycardia, when known; and 
          • (4) is followed by fatigue. 
      • Primary Autonomic Failure 
      • Secondary Autonomic Failure 

      • Drug-Induced OH
      • Volume Depletion
      • Postural Tachycardia Syndrome (POTS)
        • HR > 30 bpm after > 30 sec of standing ( > 40 sec form age 12 -19)
        • Pure POTS has no orthostasis 
          • Mnt:
            • Clonidine or alpha-methyldopa  in patients with prominent hyperadrenergic features 
          • Mechanism
            • autonomic denervation, 
            • hypovolemia, 
            • hyperadrenergic stimulation, 
            • reconditioning, and 
            • hypervigilance, 
      • Progressive OH
      • Classic vs Initial OH
        • Initial > 40 mmhg fall < 30 sec, 
        • Seen in younger patients


    • Neurocardiogenic or Reflexly mediated Syncope 
      • Definition:
        • Upright posture > 30 sec, or emotional stress ordain. Related boradycardio, hypotension, and is followed by fatigue 
      • Mechanism
        • Not fully understood
        • Bezold-Jarish Reflex

    • Workup
      • When to use ILR
        • Unexplained syncope
        • Esp in older patients 
References on Orthostatic Hypotension



   











 







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