Infective Endocarditis (-itis: inflammation)
- Communication is the key
- incidence: 10-20 K (15 % are in prosthetic valve)
- Mortality: 20 %
- Pathogen
- Pathogenesis:
- Anatomy:
- Skin exam:
- Can be missed for vasculitis
- Nomenclature:
- Duke 1: 2D criteria included
- Modified Duke : TEE included
- Note: If TEE misses, CTA can be done
- Changing in imaging is more important than one time imaging finding. Hence, follow up is needed.
- Diagnosis:
- 3 sets of blood culture before antibiotics can identify organism in 85 % of the case
- Culture negative:
- Tryponemal Whippeli
- Bartoneall henscele
- P ace > 10 day of blood culture
- Histology:
- Fungal serology
- PCR sequencing: sent to Uni of Washington.
- Everyone gets Head CT
- CT chest (if device, or
- CT abd
- Splenic abscess vs infarct
- Surgical staging is different
- References:
Infective Endocarditis
Circulation. 2007;116:1736-1754.
Circulation. 2007;116:1736-1754.
Circulation. 2007;116:1736-1754.
Device Infection
Circulation. 2010;121:458-477.
Circulation. 2010;121:458-477.
Circulation. 2010;121:458-477.
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