CI and Neurology

GBS MS  Patient with relapse of MS? How do you manage such patient?  Questions to answer are:  Is MS a single clinical entity? What is the pathophysiology of MS? What are the treatment strategies, and how do they work?  Questions not to be discussed are:   Diagnostic criteria of MS: See under Neurology Phenotypic Charaterization of MS: See under Neurology Multiple Sclerosis  Pathophysiology:  Etiology: Unknown Pathological Pattern: Not uniform Macrophage infiltration Microgial Activation Lymphocyte Infiltration Demylination Oligodendrocytes loss Axonal Damage / or Loss Multiple Sclerosis — The Plaque and Its Pathogenesis NEJM 2006  How does Fingolimoid work?  Fingolimod for Multiple Sclerosis NEJM 2012 Fingolimod for Multiple Sclerosis NEJM 2012 Fingolimod for Multiple Sclerosis NEJM 2012