Pathogeneisis of Fever
Causes of FUO Causes of Recurrent FUO Case Discussion: 71 yo AAM with hx of SCL, present with fever of 1 day. 101 F. Persist. Started on Vanc and Zosyn. Fever persists. ANC 650. Neupogen given. ANC > 1500. Fever persists. Procalcitonin: > 100, CRP > 30, Ferritin > 10,000, NK cell increased by 43 %, IL-2 receptor elevated. Has Splenomegaly that is same as it was 3 years back. Pan CT is normal except for few mediasteinal LN. BM Bxp is normal. Scheduled steroids is started, fever subsides for few days, before fever recurs. All cx are negative. What to do? Patient has few monocytes in the circulation. Could this be systemic mastocytosis. Less likely. Below is the symptoms and clinical disease manifestations of Mast cell disease. It releases histamines, and many symptoms are related to that. Could this be Malignant Histiocytosis? What is histiocytosis? http://emedicine.medscape.com/article/958026-clinical#b4 The histiocytoses encompass a group of diverse disorders characterized by the accumulation and infiltration of variable numbers of monocytes, macrophages, and dendritic cells in the affected tissues. The classification of histiocytic disorders the World Health Organization (WHO) has proposed is as follows:
Heat Stroke vs Heat Exhuastion  |
