Pulmonary
GLILD seen in patient with CVID has 3 various type of histopathology in a same patient. It is different from Sarcoidosis. Sarcoid nodule are smaller than that seen in GL-ILD. Normal PFT, and CXR does not rule out the presence of GL - ILD Nodular Lymphoid Hyperplasia If seen is suggestive of CVID IgA deficiency, and Autoimmunity 1/600 Autoimmunity in upto 35 % 23 % of group identified from healthy blood donor developed autoimmune disease over 20 years Autoimmune manifestation of coplement deficiency Majority will develop SLE |